Discussions



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  Session I: The state of structural biology of large structures
   
 

Helen Saibil
 Birkbeck College
 Moderator
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Richard Henderson
 of Molecular Biology
 MRC–Laboratory
The power of electron cryomicroscopy

 
 
 
  The Ribosome--a molecular machine in motion
   
 

Joachim Frank
 Howard Hughes Medical Center
 Wadsworth Center
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  Biochemical basis for x-ray crystallography of the ribosome
   
 

Jamie Cate
 University of California
 Berkeley
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  Session II: Extending x-ray crystallography to ever larger structures
   
 

Keith Hodgson
 Moderator
 Stanford University
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Andrew Thompson
 EMBL
 Grenoble
Can we routinely collect useful data from micro-crystals?

 
 
 
  Future X-ray sources (tentative)
   
 

Janos Hajdu
 Upsala University
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  The phase problem: does size matter?
   
 

Randy Reed
 University of Cambridge
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  Session III: What does the future hold for electron cryomicroscopy?
   
 

Bob Glaeser
 Moderator
 University of California Berkeley
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Niko Grigorieff
 Brandeis
 University
Single particles always fit the mold

 
 
 
  Tubulin and Microtubule Structures - Combining Crystallographic and Single Particle Approaches
   
 

Ken Downing
 Lawrence Berkeley Laboratory
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  Electron Tomography: Towards visualizing macromolecular assemblies inside cells
   
 

Wolfgang Baumeister
 Max-Planck Institute
 Martinsried
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  Polymorphism, can we detect it? Can we use it? Can we control it?
   
 

Edward Egelman
 University of Virginia Health Science Center
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  Session IV: Can hybrid methods provide credible atomic models?
   
 

Eva Nogales
 Moderator
 University of California Berkeley
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Michael Rossman
 Purdue University
Combining electron microscopic with x-ray crystallographic structures

 
 
 
  Reconciling Shape with Structure: Morphometric Strategies for Multi-Resolution Flexing
   
 

Willy Wriggers
 Scripps Research Institute
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  Atomic model of the cell: docking in a tomographic environment
   
 

Niels Volkmann
 Burnham Institute
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  Consistency of 3D reconstructions in single particle analysis
   
 

Pawel Penczek
 University of Texas
 Houston Medical School
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  Session V: Computational methods
   
 

Axel Brunger
 Moderator
 Stanford University
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Andrej Sali
 Rockefeller University
Modeling of molecular assemblies by satisfaction of constraints

 
 
 
  Probing the structural and energetic basis of protein-protein interactions
   
 

Barry Honig
 Columbia University
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